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Hypophosphatasia: Evaluation of Size and Mineral Density of Exfoliated Teeth

Authors :
J Sakai
Natsuko Numa-Kinjoh
Shoko Kinoshita-Kawano
Junko Matsuyama
T Sano-Asahito
Sachiko Hayashi-Sakai
Makoto Sakamoto
Tomoe Mitomi
Source :
Journal of Clinical Pediatric Dentistry. 40:496-502
Publication Year :
2016
Publisher :
MRE Press, 2016.

Abstract

Objective: Most cases of hypophosphatasia (HPP) exhibit early loss of primary teeth. Results of micro-computed tomography (micro-CT) analysis of teeth with HPP have not yet been reported. The purpose of the present study was to describe the size and mineral density distribution and mapping of exfoliated teeth with HPP using micro CT. Study design: Seven exfoliated teeth were obtained from a patient with HPP. Exfoliated teeth sizes were measured on micro CT images and mineral densities of the mandibular primary central incisors were determined. Results: Partial dentures were fabricated for the patient to replace the eight primary teeth which had exfoliated. Most primary teeth sizes were within the normal range. The mean values of enamel and dentin mineral densities in teeth with HPP were 1.35 and 0.88 g/cm3, respectively, in the mandibular primary central incisors. Conclusion: Mineral density distribution and mapping revealed that the values in teeth with HPP were lower than the homonymous teeth controls in all regions from the crown to apex. Furthermore, it was demonstrated that the differences between HPP and controls were larger on the crown side and the differences tended to converge on the apex side. These results suggested that the present patient showed mild hypomineralization in the primary dentition.

Details

ISSN :
15575268 and 10534628
Volume :
40
Database :
OpenAIRE
Journal :
Journal of Clinical Pediatric Dentistry
Accession number :
edsair.doi.dedup.....af20674200c5184c99c5646bb5799628