A Hydroquinone Solution in the Treatment of Melasma

Two versions of a 3% hydroquinone solution in a hydroalcoholic solution were tested in 46 patients with melasma. The more effective of the two solutions tested, Formula A, was found to produce improvement in 88% of the patients, with moderate to marked improvement in 36% of them with minimal side effects. The usage of a sunscreen agent seems to be necessary for therapeutic efficacy.