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Extra-corporeal life support for near-fatal multi-drug intoxication: a case report
- Source :
- Journal of Medical Case Reports, Vol 5, Iss 1, p 231 (2011), Journal of Medical Case Reports
- Publication Year :
- 2011
- Publisher :
- Springer Science and Business Media LLC, 2011.
-
Abstract
- Introduction Severe mixed β-blocker and calcium channel blocker intoxication presents a significant risk for patient mortality. Although treatment is well-established, it sporadically fails to support the patient through massive overdoses, thus requiring non-conventional treatments. We report the use of extra-corporeal life support in a patient with refractory hemodynamic impairment due to multi-drug intoxication. Although sometimes used in clinical practice, extra-corporeal membrane oxygenation for intoxications has rarely been reported. Case presentation A 36-year-old Caucasian man presented to our hospital with refractory hypotension, severe cardiac insufficiency and multi-organ failure due to mixed intoxication with atenolol, nifedipine, Lacidipine and sertraline. Together with standard treatment, we performed extra-corporeal membrane oxygenation to overcome refractory cardiogenic shock and lead the patient to achieve a full recovery. Conclusion Standard of care for β-blocker and calcium channel blocker intoxication is well-defined and condensed into protocols of treatment. Although aimed at clearing the noxious agents from the patient's system, standard measures may fail to provide adequate hemodynamic support to allow recovery. In selected cases, extra-corporeal membrane oxygenation could be considered a bridge to drug clearance while preventing multi-organ failure due to profound shock.
- Subjects :
- Pediatrics
medicine.medical_specialty
medicine.drug_class
lcsh:Medicine
Case Report
Calcium channel blocker
Nifedipine
medicine
MED/41 - ANESTESIOLOGIA
Medicine(all)
extra-corporeal membrane oxygenation, intoxication, calcium channel blocker,cri
business.industry
Medicine (all)
Cardiogenic shock
Standard treatment
lcsh:R
General Medicine
Refractory hypotension
medicine.disease
Lacidipine
Life support
Anesthesia
Shock (circulatory)
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 17521947
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of Medical Case Reports
- Accession number :
- edsair.doi.dedup.....af1568f2d468271f1345786a72dc4887