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Heart Rate in Patients with SARS-CoV-2 Infection: Prevalence of High Values at Discharge and Relationship with Disease Severity
- Source :
- Journal of Clinical Medicine, Journal of Clinical Medicine; Volume 10; Issue 23; Pages: 5590, Journal of Clinical Medicine, Vol 10, Iss 5590, p 5590 (2021)
- Publication Year :
- 2021
-
Abstract
- The most common arrhythmia associated with COronaVIrus-related Disease (COVID) infection is sinus tachycardia. It is not known if high Heart Rate (HR) in COVID is simply a marker of higher systemic response to sepsis or if its persistence could be related to a long-term autonomic dysfunction. The aim of our work is to assess the prevalence of elevated HR at discharge in patients hospitalized for COVID-19 and to evaluate the variables associated with it. We enrolled 697 cases of SARS-CoV2 infection admitted in our hospital after February 21 and discharged within 23 July 2020. We collected data on clinical history, vital signs, laboratory tests and pharmacological treatment. Severe disease was defined as the need for Intensive Care Unit (ICU) admission and/or mechanical ventilation. Median age was 59 years (first-third quartile 49, 74), and male was the prevalent gender (60.1%). 84.6% of the subjects showed a SARS-CoV-2 related pneumonia, and 13.2% resulted in a severe disease. Mean HR at admission was 90 ± 18 bpm with a mean decrease of 10 bpm to discharge. Only 5.5% of subjects presented HR > 100 bpm at discharge. Significant predictors of discharge HR at multiple linear model were admission HR (mean increase = β = 0.17 per bpm, 95% CI 0.11; 0.22, p < 0.001), haemoglobin (β = −0.64 per g/dL, 95% CI −1.19; −0.09, p = 0.023) and severe disease (β = 8.42, 95% CI 5.39; 11.45, p < 0.001). High HR at discharge in COVID-19 patients is not such a frequent consequence, but when it occurs it seems strongly related to a severe course of the disease.
- Subjects :
- medicine.medical_specialty
Sinus tachycardia
medicine.medical_treatment
Vital signs
heart rate
SARS-CoV-2
infection severity
COVID-19
Article
law.invention
Sepsis
law
Internal medicine
Heart rate
medicine
Mechanical ventilation
business.industry
General Medicine
medicine.disease
Intensive care unit
Pneumonia
Quartile
Medicine
medicine.symptom
business
Subjects
Details
- ISSN :
- 20770383
- Volume :
- 10
- Issue :
- 23
- Database :
- OpenAIRE
- Journal :
- Journal of clinical medicine
- Accession number :
- edsair.doi.dedup.....af14309a68e0f02c1b861265d68bd59f