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Core outcome sets in dermatology: report from the second meeting of the International Cochrane Skin Group Core Outcome Set Initiative

Authors :
Kottner, J
Jacobi, L
Hahnel, E
Alam, M
Balzer, K
Beeckman, D
Busard, C
Chalmers, J
Deckert, S
Eleftheriadou, V
Furlan, K
Horbach, SER
Kirkham, J
Nast, A
Spuls, P
Thiboutot, D
Thorlacius, L
Weller, K
Williams, HC
Schmitt, J
Outcome, Int Cochrane Skin Grp Core
APH - Quality of Care
APH - Methodology
APH - Personalized Medicine
AII - Inflammatory diseases
Graduate School
Dermatology
AII - Amsterdam institute for Infection and Immunity
ACS - Diabetes & metabolism
Source :
BRITISH JOURNAL OF DERMATOLOGY, British journal of dermatology, 178(4), e279-e285. Wiley-Blackwell, British Journal of Dermatology, International Cochrane Skin Group Core Outcome Set Initiative (CSG-COUSIN) group 2018, ' Core outcome sets in dermatology : report from the second meeting of the International Cochrane Skin Group Core Outcome Set Initiative ', The British journal of dermatology, vol. 178, no. 4, pp. e279-e285 . https://doi.org/10.1111/bjd.16324
Publication Year :
2017

Abstract

Summary Results of clinical trials are the most important information source for generating external clinical evidence. The use of different outcomes across trials, which investigate similar interventions for similar patient groups, significantly limits the interpretation, comparability and clinical application of trial results. Core outcome sets (COSs) aim to overcome this limitation. A COS is an agreed standardized collection of outcomes that should be measured and reported in all clinical trials for a specific clinical condition. The Core Outcome Set Initiative within the Cochrane Skin Group (CSG-COUSIN) supports the development of core outcomes in dermatology. In the second CSG-COUSIN meeting held in 2017, 11 COS development groups working on skin diseases presented their current work. The presentations and discussions identified the following overarching methodological challenges for COS development in dermatology: it is not always easy to define the disease focus of a COS; the optimal method for outcome domain identification and level of detail needed to specify such domains is challenging to many; decision rules within Delphi surveys need to be improved; appropriate ways of patient involvement are not always clear. In addition, there appear to be outcome domains that may be relevant as potential core outcome domains for the majority of skin diseases. The close collaboration between methodologists in the Core Outcome Set Initiative and the international Cochrane Skin Group has major advantages for trialists, systematic reviewers and COS developers.

Details

ISSN :
13652133 and 00070963
Volume :
178
Issue :
4
Database :
OpenAIRE
Journal :
The British journal of dermatology
Accession number :
edsair.doi.dedup.....aef971cd19755f637549b51cfe90edd3
Full Text :
https://doi.org/10.1111/bjd.16324