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Prognostic significance of the number of lymph nodes in elective neck dissection for tongue and mouth floor cancers
- Source :
- Brazilian Journal of Otorhinolaryngology v.78 n.2 2012, Brazilian Journal of Otorhinolaryngology, Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF), instacron:ABORL-CCF, Brazilian Journal of Otorhinolaryngology, Volume: 78, Issue: 2, Pages: 22-26, Published: APR 2012
- Publication Year :
- 2012
- Publisher :
- Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial., 2012.
-
Abstract
- A presença de linfonodos metastáticos é aspecto relevante no tratamento do câncer na cabeça e pescoço, resultando em 50% de redução na sobrevida. OBJETIVO: Avaliar o número de linfonodos removidos no esvaziamento cervical e sua relação com o prognóstico. MÉTODOS: Estudo retrospectivo de 143 pacientes portadores de carcinoma epidermoide de língua e soalho bucal, cujo exame histológico evidenciou ausência de metástases linfonodais. Desses, 119 eram masculinos e 24 femininos, com idade média de 54 anos. Quanto ao sítio do tumor primário, 65 eram na língua e 78 no soalho bucal. A distribuição do estádio T foi de quatro T1, 84 T2, 36 T3 e 19 T4. Foram realizados 176 esvaziamentos cervicais, sendo unilateral em 110 casos e bilateral em 33. Desses, 78 radicais e 98 seletivos. Os pacientes foram separados em três grupos, de acordo com os percentis 33 e 66 do número de linfonodos ressecados. RESULTADOS: O número médio de linfonodos ressecados foi de 27, sendo 24 nos esvaziamentos seletivos e 31 nos completos. Não foram observadas diferenças estatisticamente significantes quando relacionado aos estádios T e N. CONCLUSÕES: O maior número de linfonodos dissecados no esvaziamento cervical identifica um grupo de melhor prognóstico nos casos pN0. The presence of metastatic lymph nodes is a relevant aspect in the treatment of head and neck cancer, bringing about a 50% reduction in survival. OBJECTIVE: To assess the number of lymph nodes removed in the neck dissection and their relationship with the prognosis. METHODS: A retrospective study involving 143 patients with tongue and mouth floor epidermoid carcinoma, which histological exam showed no lymph node metastases. Among those, 119 were males and 24 females, with mean age of 54 years. As to the primary tumor site, 65 were in the tongue and 78 in the mouth floor. T stage distribution was of four T1, 84 T2, 36 T3 and 19 T4. We carried out 176 neck dissections, unilateral in 110 cases and bilateral in 33. Of these, 78 were radical and 98 selective. The patients were broken down into three groups, according to the 33 and 66 percentiles of the number of lymph nodes resected. RESULTS: The mean number of resected lymph nodes was 27; 24 in selective dissections and 31 in the complete ones. We did not have statistically significant differences when associated to the T and N stages. CONCLUSIONS: The larger number of lymph nodes dissected in the neck dissection identifies the group of better prognoses among pN0 cases.
- Subjects :
- medicine.medical_specialty
esvaziamento cervical
squamous cells
medicine.medical_treatment
carcinoma
neoplasias bucais
carcinoma de células escamosas
Tongue
lymph nodes
medicine
Lymph node
neck dissection
Pharmacology
Mouth neoplasm
business.industry
mouth neoplasms
Head and neck cancer
linfonodos
Neck dissection
medicine.disease
Primary tumor
medicine.anatomical_structure
Epidermoid carcinoma
Radiology
Lymph
business
Subjects
Details
- Language :
- Portuguese
- Database :
- OpenAIRE
- Journal :
- Brazilian Journal of Otorhinolaryngology v.78 n.2 2012, Brazilian Journal of Otorhinolaryngology, Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF), instacron:ABORL-CCF, Brazilian Journal of Otorhinolaryngology, Volume: 78, Issue: 2, Pages: 22-26, Published: APR 2012
- Accession number :
- edsair.doi.dedup.....aeeb8fb6ca3ec1a985fd0f1a02961c47