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Supplementary Tables 1 - 20 from A Surprising Cross-Species Conservation in the Genomic Landscape of Mouse and Human Oral Cancer Identifies a Transcriptional Signature Predicting Metastatic Disease

Authors :
Ravindra Uppaluri
Elaine R. Mardis
James S. Lewis
Jay F. Piccirillo
Gavin P. Dunn
Nancy P. Judd
Dorina Kallogjeri
Charles G. Rickert
Jonathan H. Law
Varun Chalivendra
Krishna-Latha Kanchi
Ashley E. Winkler
Michael D. Onken
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

XLS file - 6534KB, S1 SNVs indolent lines. S2 SNVs aggressive lines. S3 Distribution of nucleotide changes. S4 MOC line mutations have similarity to 32 most common HNSCC TCGA mutations. S5 MOC line conservation with human OSCC drivers and novel mutations. S6 Indels all MOC lines. S7 Comparison of predicted changes between aggressive and indolent lines. S8 MOC line common mutations. S9 Unique aggressive MOC line mutations. S10 Comparison of MOC line mutations with TCGA N0 and N+ mutations. S11 TCGA mutation burden per tumor in N0 and N+ specimens. S12 MOC line and TCGA common mutations. S13 Rate of alterations of aggressive MOC/TCGA N+ mutations from Table S10. S14 Rate of alterations of indolent MOC/TCGA N0 mutations from Table S10. S15 SAM analysis of aggressive versus indolent expression data. S16 Compiled rank metric scores of OCAMP-A genes across three human datasets. S17 Cross tabulation and multivariable analysis of OCAMP-B on MD dataset. S18 Weighted voting classification with OCAMP-B on independent UPENN dataset. S19 SVM output data for training and test sets. S20 OCAMP-A comparison to three published signatures.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....aee43dc7b187f08473545afb67d20f84
Full Text :
https://doi.org/10.1158/1078-0432.22454639