Absence of any adverse effect of inadvertent ivermectin treatment during pregnancy

Although ivermectin is safe and well tolerated when distributed through mass treatment, pregnancy remains the major contraindication. PACQUE et al. (1990) considered that about half of the women in the first trimester of pregnancy might be treated inadvertently during community-based distribution of ivermectin, and stated that rates of miscarriage, stillbirth or major congenital malformation were not significantly different between treated and untreated women, During a mass treatment campaign for onchocerciasis in the Vina valley, North Cameroon, 2710 women from 15 to 45 vears old received ivermectin. Of 1495 women treated tre at ed