Serum uromodulin is associated with urinary albumin excretion in adolescents with type 1 diabetes

Authors :: David M. Maahs
R. Paul Wadwa
Richard J. Johnson
Tyler Lipina
Carlos Roncal
David Z.I. Cherney
Franziska K. Bishop
Laura Pyle
Petter Bjornstad
Pattara Wiromrat
Source :: J Diabetes Complications
Publication Year :: 2019
Publisher :: Elsevier BV, 2019.
Abstract: Early diabetic kidney disease (DKD) occurs in adolescents with type 1 diabetes (T1D). Lower serum uromodulin (SUMOD) predicts DKD progression in adults with T1D. In this study, we demonstrate that lower SUMOD is associated with urinary albumin excretion in adolescents with T1D, suggesting a potential relationship between SUMOD and early kidney dysfunction in T1D youth.

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