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Long-Term Prognosis of Patients with Large Subcortical Infarctions
- Source :
- European Neurology. 62:304-310
- Publication Year :
- 2009
- Publisher :
- S. Karger AG, 2009.
-
Abstract
- Aim: We assessed the long-term prognosis of patients with large subcortical infarctions (LSCI). Methods: We defined LSCI as lesions ≥15 mm confined to deep penetrating arteries without a cardioembolic or atherothrombotic source. Patients with acute ischemic strokes were consecutively registered and followed for 751 ± 441 days. The clinical characteristics and long-term prognoses of patients with LSCI were compared to those of patients with lacunar (LACI), atherothrombotic (ATI) and cardioembolic infarctions (CEI). Results: At discharge from the hospital, the proportion of good outcomes (modified Rankin Scale ≤2) for patients with LSCI (52.1%) was similar to that for ATIs (47.2%), but worse than that for LACIs (73.2%). After a 3-year follow-up period, the mortality rates from LSCI, LACIs, ATIs and CEIs were 8.4, 8.2, 22.3 and 41.1%, respectively; the recurrence rates were 9.3, 14.1, 16.6 and 23.8%, respectively. Conclusions: The short-term prognosis of functional outcomes for LSCI was worse than that for LACIs, but similar to acute-phase ATI outcomes. The long-term prognosis after a LSCI is good, and recurrence tends to be lower than for LACIs.
- Subjects :
- Male
medicine.medical_specialty
Severity of Illness Index
Disability Evaluation
Recurrence
Modified Rankin Scale
Internal medicine
Severity of illness
Humans
Medicine
Prospective cohort study
Survival analysis
Aged
Aged, 80 and over
Subcortical Infarctions
business.industry
Cerebral infarction
Patient Selection
Mortality rate
Ischemic strokes
Cerebral Infarction
Middle Aged
Prognosis
medicine.disease
Survival Analysis
Surgery
Treatment Outcome
Neurology
Disease Progression
Cardiology
Female
Neurology (clinical)
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 14219913 and 00143022
- Volume :
- 62
- Database :
- OpenAIRE
- Journal :
- European Neurology
- Accession number :
- edsair.doi.dedup.....ae3fb74eb1c64989339d4c2a6da9b5ea