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Cerebellar activation during a motor task in conversion disorder with motor paralysis: A case report and fMRI study
- Source :
- Neuropsychopharmacology Reports
- Publication Year :
- 2018
- Publisher :
- Wiley, 2018.
-
Abstract
- Background Motor conversion disorders are characterized by movement symptoms without a neurological cause. A psychogenic etiology is presumed for these disorders, but little is known about their underlying neural mechanisms. Functional magnetic resonance imaging (fMRI) has been utilized to understand the mechanisms associated with unexplained motor symptoms. Here, we used fMRI to investigate the cerebral response to motor stimulation in a patient with conversion disorder with motor paralysis to determine the underlying neural mechanisms of this disorder. Methods Brain activation induced by movements of the bilateral ankle joints (repeated plantar flexion and dorsiflexion) was recorded using fMRI in a patient with conversion disorder with unexplained motor paralysis. We acquired 2 types of imaging data: (i) data obtained while motor paralysis remained present and (ii) data obtained after motor paralysis had completely improved. We used a within‐subject fMRI block design to compare the patient's brain activities during the motor task and at rest. Results Cerebral motor areas were significantly activated during the motor task relative to at rest, both when motor paralysis remained present and when paralysis had improved (FWE‐corrected P<br />The complementary abnormal function in the cerebellum might be associated with the neural basis of conversion disorder with motor paralysis, as with cases of stroke.
- Subjects :
- Cerebellum
medicine.medical_specialty
cerebellum
Case Report
Case Reports
03 medical and health sciences
0302 clinical medicine
Physical medicine and rehabilitation
motor task
motor paralysis
Paralysis
medicine
Psychogenic disease
Pharmacology (medical)
Conversion disorder
Pharmacology
medicine.diagnostic_test
business.industry
conversion disorder
medicine.disease
Lobe
Psychiatry and Mental health
Clinical Psychology
Motor task
medicine.anatomical_structure
030220 oncology & carcinogenesis
functional MRI
medicine.symptom
Ankle
Functional magnetic resonance imaging
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 2574173X
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- Neuropsychopharmacology Reports
- Accession number :
- edsair.doi.dedup.....ae0d2edaa2ff53d41eeef3cf855cf83b
- Full Text :
- https://doi.org/10.1002/npr2.12008