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Somatosensory Amplification Is a Predictor of Self-Reported Side Effects in the Treatment of Primary Hypertension: a Pilot Study
- Source :
- International Journal of Behavioral Medicine. 23:327-332
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- Side effects consist of drug-specific and non-specific symptoms. Both components are based on bodily sensations that a person perceives after taking a drug and subsequently attributes to the drug. We suggest that somatosensory amplification (SSA) may explain a proportion of inter-individual differences in reports of side effects that cannot be accounted for by drug-specific safety profiles. This hypothesis was investigated in hypertensive patients starting a new pharmacotherapy. This longitudinal study included 50 patients (66 % women, aged 55 ± 14 years) with a diagnosis of primary hypertension. Patients completed the Somatosensory Amplification Scale (SSAS), started to take their new medication, and recorded side effects on a daily basis for 4 weeks. After controlling for age, gender, number of pills taken, and previous personal and family experiences with medication side effects in the regression analyses, SSAS scores remained a significant predictor of reported side effects over the entire study period (weeks 1 and 2: β = .621, p
- Subjects :
- Adult
Male
Longitudinal study
medicine.medical_specialty
Nocebo
Sensation
Pilot Projects
03 medical and health sciences
0302 clinical medicine
Pharmacotherapy
Informed consent
Internal medicine
medicine
Humans
Longitudinal Studies
030212 general & internal medicine
Psychiatry
Antihypertensive Agents
Applied Psychology
Aged
business.industry
Somatosensory amplification
Middle Aged
Health psychology
Pill
Hypertension
Regression Analysis
Female
Self Report
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 15327558 and 10705503
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- International Journal of Behavioral Medicine
- Accession number :
- edsair.doi.dedup.....adeb06cd86b6c9d4fa71e03eca54c0a2
- Full Text :
- https://doi.org/10.1007/s12529-016-9536-0