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Somatosensory Amplification Is a Predictor of Self-Reported Side Effects in the Treatment of Primary Hypertension: a Pilot Study

Authors :
György Bárdos
Bettina K. Doering
Ferenc Köteles
Judit Szécsi
Source :
International Journal of Behavioral Medicine. 23:327-332
Publication Year :
2016
Publisher :
Springer Science and Business Media LLC, 2016.

Abstract

Side effects consist of drug-specific and non-specific symptoms. Both components are based on bodily sensations that a person perceives after taking a drug and subsequently attributes to the drug. We suggest that somatosensory amplification (SSA) may explain a proportion of inter-individual differences in reports of side effects that cannot be accounted for by drug-specific safety profiles. This hypothesis was investigated in hypertensive patients starting a new pharmacotherapy. This longitudinal study included 50 patients (66 % women, aged 55 ± 14 years) with a diagnosis of primary hypertension. Patients completed the Somatosensory Amplification Scale (SSAS), started to take their new medication, and recorded side effects on a daily basis for 4 weeks. After controlling for age, gender, number of pills taken, and previous personal and family experiences with medication side effects in the regression analyses, SSAS scores remained a significant predictor of reported side effects over the entire study period (weeks 1 and 2: β = .621, p

Details

ISSN :
15327558 and 10705503
Volume :
23
Database :
OpenAIRE
Journal :
International Journal of Behavioral Medicine
Accession number :
edsair.doi.dedup.....adeb06cd86b6c9d4fa71e03eca54c0a2
Full Text :
https://doi.org/10.1007/s12529-016-9536-0