Gestational Diabetes Mellitus in HIV-Infected and -Uninfected Pregnant Women in Cameroon

Gestational diabetes mellitus (GDM) in both HIV-infected and -uninfected women has been poorly studied in Africa. We enrolled pregnant women ages 15–50 years at a large semiurban clinic in Cameroon. A 75-g oral glucose tolerance test (OGTT) was performed at 24–28 weeks' gestational age or at the earliest prenatal visit for those presenting after 28 weeks. Women were diagnosed with GDM according to American Diabetes Association criteria (1). Data on height, blood pressure, sociodemographics, obstetrical history, prepregnancy weight, HIV clinical status, combination antiretroviral therapy (cART) history, and pregnancy outcomes were collected. Exact logistic regression models were used to identify predictors of GDM. Of 316 participants, 20 (63%) had GDM, and 3 had overt diabetes (DM). Women with GDM presented for OGTT later than those without (29 vs. 27 weeks, P = 0.04) (Table 1). After adjustment for age, gestational age at the time of OGTT, family history of DM, HIV, …