Back to Search
Start Over
Reorganization of Nuclear Pore Complexes and the Lamina in Late-Stage Parvovirus Infection
- Publication Year :
- 2015
- Publisher :
- American Society for Microbiology, 2015.
-
Abstract
- Article<br />Canine parvovirus (CPV) infection induces reorganization of nuclear structures. Our studies indicated that late-stage infection induces accumulation of nuclear pore complexes (NPCs) and lamin B1 concomitantly with a decrease of lamin A/C levels on the apical side of the nucleus. Newly formed CPV capsids are located in close proximity to NPCs on the apical side. These results suggest that parvoviruses cause apical enrichment of NPCs and reorganization of nuclear lamina, presumably to facilitate the late-stage infection.<br />published version<br />http://purl.org/eprint/status/PeerReviewed
- Subjects :
- Parvovirus, Canine
animal diseases
viruses
nuclear pore complexes
Immunology
Microbiology
Parvoviridae Infections
Capsid
Dogs
Virology
medicine
otorhinolaryngologic diseases
Animals
Dog Diseases
Nuclear pore
parvovovirus
Cell Nucleus
Nuclear Lamina
Lamin Type B
biology
Parvovirus
Parvovirus infection
Canine parvovirus
Lamin Type A
biology.organism_classification
medicine.disease
Virus-Cell Interactions
Cell biology
Nuclear Pore Complex Proteins
Cell nucleus
stomatognathic diseases
medicine.anatomical_structure
Insect Science
Nuclear Pore
Nuclear lamina
Nucleus
Lamin
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....ad97d786a61945d5bfbcd9cf4018112e