Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2

Authors :: David R. Cox
Marcel J. T. Reinders
Jeroen van Rooij
Joris Deelen
P. Eline Slagboom
Jeanine J. Houwing-Duistermaat
Anton J. M. de Craen
Shobha Potluri
Matthijs Moed
Erik B. van den Akker
Nico Lakenberg
Marian Beekman
Robert Kraaij
André G. Uitterlinden
Steven J. Pitts
Joyce B. J. van Meurs
Albert Hofman
Gert-Jan B. van Ommen
Wesley J. de Dijcker
H. Eka D. Suchiman
Biological Psychology
APH - Personalized Medicine
APH - Health Behaviors & Chronic Diseases
APH - Methodology
APH - Mental Health
Internal Medicine
Epidemiology
Source :: Blood, van den Akker, E B, Pitts, S J, Reinders, M J T, Slagboom, P E, Genome of the Netherlands Consortium, Abdellaoui, A, Hottenga, J J, Kattenberg, M, Boomsma, D & Willemsen, G 2016, ' Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2 ', Blood, vol. 127, no. 11, pp. 1512-5 . https://doi.org/10.1182/blood-2015-12-685925, Blood, 127(11), 1512-1515, Blood, 127(11), 1512-5. American Society of Hematology, Blood, 127(11), 1512-1515. American Society of Hematology
Publication Year :: 2016
Abstract: To the editor: Recent large-scale sequencing studies report recurrent somatic mutations in the blood of elderly individuals in genes previously linked to clonal expansion of hematopoietic stem cells.[1][1][⇓][2][⇓][3]-[4][4] Particularly for DNMT3A and TET2 , a steep age-associated increase in

ISSN :: 00064971
Database :: OpenAIRE
Journal :: Blood, van den Akker, E B, Pitts, S J, Reinders, M J T, Slagboom, P E, Genome of the Netherlands Consortium, Abdellaoui, A, Hottenga, J J, Kattenberg, M, Boomsma, D & Willemsen, G 2016, ' Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2 ', Blood, vol. 127, no. 11, pp. 1512-5 . https://doi.org/10.1182/blood-2015-12-685925, Blood, 127(11), 1512-1515, Blood, 127(11), 1512-5. American Society of Hematology, Blood, 127(11), 1512-1515. American Society of Hematology
Accession number :: edsair.doi.dedup.....ad81dba24bfea597c82121207c24c5d5
Full Text :: https://doi.org/10.1182/blood-2015-12-685925

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