Supplementary Figures from Proteomic Profiling of the ECM of Xenograft Breast Cancer Metastases in Different Organs Reveals Distinct Metastatic Niches

Supplementary Figures S1 to S10. Supplementary Figure S1. Quality control western blots; Supplementary Figure S2. Label-free matrisome protein abundance; Supplementary Figure S3. Label-free percentage protein abundance; Supplementary Figure S4. Proteins identified in only one TMT 10-plex; Supplementary Figure S5. Tumor-cell-only proteins; Supplementary Figure S6. Abundance of tumor-cell-derived and stroma-derived matrisome proteins in metastases to different tissues; Supplementary Figure S7. Stromal proteins elevated in metastases relative to normal tissue; Supplementary Figure S8. Alterations in SERPINB1 are associated with lower progression-free survival; Supplementary Figure S9. Additional proteins evaluated for altered metastatic tropism; Supplementary figure S10. Gene Set Enrichment Analysis of ECM proteins and predicted upstream regulators in brain metastases.