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Immunotherapeutic effects of chitin in comparison with chitosan against Leishmania major infection
- Source :
- Parasitology International. 65:99-104
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- Chitin and chitosan microparticles (MPs) are important immune system stimulators. The aim of this study was to evaluate the protective effects of these compounds in comparison with each other against Leishmania infection in BALB/c mice infected with Leishmania major (L. major). Female BALB/c mice were injected subcutaneously with 2×10(5) promastigotes. Chitin and/or chitosan MPs (
- Subjects :
- 0301 basic medicine
Leishmaniasis, Cutaneous
Chitin
macromolecular substances
Parasite Load
Chitosan
Interferon-gamma
03 medical and health sciences
chemistry.chemical_compound
Immune system
Adjuvants, Immunologic
Subcutaneous Absorption
medicine
Animals
Interferon gamma
Leishmania major
Lymph node
Cell Proliferation
Mice, Inbred BALB C
biology
Tumor Necrosis Factor-alpha
Chemistry
biology.organism_classification
Leishmania
Molecular biology
carbohydrates (lipids)
030104 developmental biology
Infectious Diseases
medicine.anatomical_structure
Immunology
Cytokines
Female
Parasitology
Immunotherapy
Lymph Nodes
Lymph
medicine.drug
Subjects
Details
- ISSN :
- 13835769
- Volume :
- 65
- Database :
- OpenAIRE
- Journal :
- Parasitology International
- Accession number :
- edsair.doi.dedup.....ad20b3860fc74557252dd0d00909398c