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Outcomes of Children Born to Pregnant Women With Drug-resistant Tuberculosis Treated With Novel Drugs in Khayelitsha, South Africa: A Report of Five Patients
- Source :
- The Pediatric Infectious Disease Journal
- Publication Year :
- 2021
- Publisher :
- Williams & Wilkins, 2021.
-
Abstract
- This brief report presents a series of 5 pregnant women treated for rifampicin-resistant tuberculosis with the novel drugs bedaquiline, delamanid, and linezolid as part of an optimized backbone regimen and reviews the outcomes of the children born to them. Although the case series is small, all children had excellent birth outcomes suggesting pregnant women should not be denied access to novel therapies for RR-TB.
- Subjects :
- Microbiology (medical)
Adult
Pediatrics
medicine.medical_specialty
Tuberculosis
MEDLINE
Antitubercular Agents
delamanid
03 medical and health sciences
chemistry.chemical_compound
South Africa
Young Adult
0302 clinical medicine
Pregnancy
030225 pediatrics
Tuberculosis, Multidrug-Resistant
medicine
Humans
Infant Health
030212 general & internal medicine
bedaquiline
Diarylquinolines
Oxazoles
business.industry
Drug resistant tuberculosis
Child Health
Linezolid
Pregnancy Outcome
Infant
medicine.disease
Regimen
Infectious Diseases
chemistry
tuberculosis
Nitroimidazoles
Child, Preschool
Pediatrics, Perinatology and Child Health
Female
Pregnant Women
Delamanid
Bedaquiline
business
medicine.drug
Maternal-Neonatal Reports
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- The Pediatric Infectious Disease Journal
- Accession number :
- edsair.doi.dedup.....acf632aafea21c4fdcdba7c377964a50