Keto-Difluoromethylation of Aromatic Alkenes by Photoredox Catalysis: Step-Economical Synthesis of α-CF2H-Substituted Ketones in Flow

Authors :: Takashi Koike
Manabu Abe
Gaku Ando
Munetaka Akita
Yoshiki Nakayama
Source :: ACS Catalysis. 9:6555-6563
Publication Year :: 2019
Publisher :: ACS, 2019.
Abstract: A step-economical method for synthesis of α-CF2H-substituted ketones from readily available alkene feedstocks has been developed. Radical difluoromethylation of aromatic alkenes combining DMSO oxid...

Subjects :: chemistry.chemical_classification
010405 organic chemistry
Chemistry
Alkene
Radical
Organic chemistry
Photoredox catalysis
General Chemistry
010402 general chemistry
01 natural sciences
Catalysis
0104 chemical sciences

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