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Endothelial Cell Density After XEN Implant Surgery: Short-term Data From the Italian XEN Glaucoma Treatment Registry (XEN-GTR)
- Source :
- Journal of Glaucoma. 30:559-565
- Publication Year :
- 2021
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2021.
-
Abstract
- PRECIS XEN implant was associated with low endothelial cell density (ECD) reduction. In fact, when combined with phacoemulsification, the reduction in ECD was similar to that expected after phacoemulsification alone. PURPOSE The purpose of this study was to assess the impact of XEN implant, either alone or in combination with phacoemulsification, on ECD. METHODS Multicenter, prospective, observational study conducted on consecutive open-angle glaucoma patients, who were enrolled in the Italian XEN Glaucoma Treatment Registry and have complete endothelial cell count data at baseline and at 6 months after implantation. The primary endpoint was the mean percentage change in ECD between baseline and month 6. RESULTS The study included 108 open-angle glaucoma eyes (68 in the XEN-solo and 40 eyes in the XEN+phaco groups) and 60 control eyes (phaco-solo group). As compared with baseline, mean (95% confidence interval, CI) ECD reduction was -5.6% (-7.0% to -4.9%), -11.3% (-13.8% to -10.9%), and -13.0% (14.8% to -11.8%) in the XEN-solo, XEN+phaco, and phaco-solo groups, respectively (P=0.0004
- Subjects :
- medicine.medical_specialty
genetic structures
Minimally invasive glaucoma surgery
XEN-GTR
medicine.medical_treatment
Glaucoma
Endothelial cell count
Implant surgery
03 medical and health sciences
0302 clinical medicine
XEN implant
Ophthalmology
medicine
Humans
Prospective Studies
Registries
Glaucoma Drainage Implants
Italian XEN Glaucoma Treatment Registry
Intraocular Pressure
Phacoemulsification
business.industry
Endothelial Cells
medicine.disease
Confidence interval
Endothelial cell density
glaucoma
Treatment Outcome
corneal endothelial cells
corneal endothelial density
Italy
minimally invasive glaucoma surgery
030221 ophthalmology & optometry
Implant
business
Glaucoma, Open-Angle
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 10570829
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Journal of Glaucoma
- Accession number :
- edsair.doi.dedup.....acc8895678723640a9462a1971fe1cb4