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Solitary Fibrous Tumor of the Prostate: A Case Report and Literature Review
- Source :
- Medicina, Medicina, Vol 57, Iss 1152, p 1152 (2021)
- Publication Year :
- 2021
- Publisher :
- MDPI, 2021.
-
Abstract
- Solitary fibrous tumors (SFTs) usually occur in the pleura and account for two-thirds of all cases; however, SFTs occurring in the prostate are extremely rare. Approximately 25 cases have been reported in the literature to date. This study reports the case of a 43-year-old man referred to our hospital with the chief complaint of a pelvic tumor after careful examination. The tumor marker levels were within normal limits. T2-weighted magnetic resonance imaging revealed a tumor, demonstrating primarily low signal intensity. It showed a capsule-like rim at the left lobe of the prostate, suggesting that the tumor was partially invading the rectal wall. Histopathological examination of needle-core biopsies showed spindle cell neoplasm with small and fusiform cells, strongly expressing signal transducer and activator of transcription 6 (STAT6) with a ramifying vascular network. Therefore, the clinical diagnosis of the patient was SFT of the prostate and robot-assisted radical prostatectomy was performed. Histopathological examination revealed that the tumor was composed of spindle cells with patternless and staghorn patterns. Immunohistochemical analysis showed a strong expression of STAT6. Furthermore, the tumor was partially positive for CD34. Therefore, the patient was diagnosed with SFT of the prostate. Two years after the initial diagnosis, the patient was alive with normal erectile function, continence status, and no evidence of the disease.
- Subjects :
- Solitary fibrous tumor
Pathology
medicine.medical_specialty
Medicine (General)
medicine.diagnostic_test
Prostatectomy
business.industry
medicine.medical_treatment
CD34
Magnetic resonance imaging
General Medicine
medicine.disease
medicine.anatomical_structure
R5-920
Prostate
rare case
medicine
Pelvic tumor
Immunohistochemistry
solitary fibrous tumor
case report
business
prostatic tumor
Tumor marker
Subjects
Details
- Language :
- English
- ISSN :
- 16489144 and 1010660X
- Volume :
- 57
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Medicina
- Accession number :
- edsair.doi.dedup.....acafeeb3250d64a77cdf61ce011c0770