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The Role of Pulmonary Veins in Cancer Progression from a Computed Tomography Viewpoint
- Source :
- Journal of Oncology, Vol 2016 (2016), Journal of Oncology
- Publication Year :
- 2016
- Publisher :
- Hindawi Limited, 2016.
-
Abstract
- Background. We studied the role of pulmonary veins in cancer progression using computed tomography (CT) scans.Methods. We obtained data from 260 patients with pulmonary vein obstruction syndrome (PVOS). We used CT scans to investigate pulmonary lesions in relation to pulmonary veins. We divided the lesions into central and peripheral lesions by their anatomical location: in the lung parenchymal tissue or pulmonary vein; in the superior or inferior pulmonary vein; and by unilateral or bilateral presence in the lungs.Results. Of the 260 PVOS patients, 226 (87%) had central lesions, 231 (89%) had peripheral lesions, and 190 (75%) had mixed central and peripheral lesions. Among the 226 central lesions, 93% had lesions within the superior pulmonary vein, either bilaterally or unilaterally. Among the 231 peripheral lesions, 65% involved bilateral lungs, 70% involved lesions within the inferior pulmonary veins, and 23% had obvious metastatic extensions into the left atrium. All patients exhibited nodules within their pulmonary veins. The predeath status included respiratory failure (40%) and loss of consciousness (60%).Conclusion. CT scans play an important role in following tumor progression within pulmonary veins. Besides respiratory distress, PVOS cancer cells entering centrally can result in cardiac and cerebral events and loss of consciousness or can metastasize peripherally from the pulmonary veins to the lungs.
- Subjects :
- medicine.medical_specialty
Pathology
Article Subject
030204 cardiovascular system & hematology
lcsh:RC254-282
Pulmonary vein
03 medical and health sciences
0302 clinical medicine
Parenchyma
medicine
Lung
Respiratory distress
business.industry
Cancer
medicine.disease
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Peripheral
medicine.anatomical_structure
Oncology
Respiratory failure
Tumor progression
030220 oncology & carcinogenesis
cardiovascular system
Radiology
business
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 16878469 and 16878450
- Volume :
- 2016
- Database :
- OpenAIRE
- Journal :
- Journal of Oncology
- Accession number :
- edsair.doi.dedup.....acafe9e3de8ad720caf215d7f00a8c47