Sensitivity of a Preclinical Alzheimer’s Cognitive Composite (PACC) to amyloid β load in preclinical Alzheimer’s disease

Authors :: Yen Ying Lim
Joanne Roberston
Victor L. Villemagne
Lisa Bransby
Christopher Fowler
Colin L. Masters
David Ames
Paul Maruff
Olivier Salvado
Karra Harrington
Peter J. Snyder
Source :: Journal of Clinical and Experimental Neuropsychology. 41:591-600
Publication Year :: 2019
Publisher :: Informa UK Limited, 2019.
Abstract: Introduction: Preclinical Alzheimer’s disease (AD) is characterized by amyloid-related cognitive decline. Reduction in this decline is used to determine the efficacy of drug therapies designed to f...

Subjects :: Male
Oncology
medicine.medical_specialty
Amyloid β
Amyloid beta
Neuroimaging
Disease
Neuropsychological Tests
Sensitivity and Specificity
050105 experimental psychology
Amyloid beta-Protein Precursor
03 medical and health sciences
0302 clinical medicine
Alzheimer Disease
Internal medicine
medicine
Humans
Cognitive Dysfunction
0501 psychology and cognitive sciences
Longitudinal Studies
Prospective Studies
Cognitive decline
Life Style
Aged
Aged, 80 and over
Mini–Mental State Examination
biology
medicine.diagnostic_test
05 social sciences
Australia
Cognition
Middle Aged
Mental Status and Dementia Tests
Prognosis
medicine.disease
Clinical neurology
Clinical Psychology
Neurology
Positron-Emission Tomography
Disease Progression
biology.protein
Female
Neurology (clinical)
Alzheimer's disease
Psychology
Biomarkers
030217 neurology & neurosurgery

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