Caffeic Acid, an Active Ingredient in Coffee, Combines with DOX for Multitarget Combination Therapy of Lung Cancer

Authors :: Xue Bai
Shuting Li
Xinyi Liu
Hailong An
Xianjiang Kang
Shuai Guo
Source :: Journal of Agricultural and Food Chemistry. 70:8326-8337
Publication Year :: 2022
Publisher :: American Chemical Society (ACS), 2022.
Abstract: Adjuvant diet therapy is an important means of comprehensive treatment of cancer. It is recognized by patients for its high safety, painlessness, and ease to operate. However, the development of adjuvant dietary therapy is limited by unclear targets and unclear anticancer mechanisms. In this work, caffeic acid was found as an inhibitor of TMEM16A with an IC

Subjects :: Molecular Docking Simulation
Caffeic Acids
Lung Neoplasms
Doxorubicin
Cell Line, Tumor
Humans
Apoptosis
General Chemistry
General Agricultural and Biological Sciences
Coffee
Xenograft Model Antitumor Assays
Cell Proliferation

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