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Near-Infrared Light Irradiation Induced Mild Hyperthermia Enhances Glutathione Depletion and DNA Interstrand Cross-Link Formation for Efficient Chemotherapy
- Source :
- ACS Nano. 14:14831-14845
- Publication Year :
- 2020
- Publisher :
- American Chemical Society (ACS), 2020.
-
Abstract
- DNA alkylating agents generally kill tumor cells by covalently binding with DNA to form interstrand or intrastrand cross-links. However, in the case of cisplatin, only a few DNA adducts (
- Subjects :
- General Physics and Astronomy
Antineoplastic Agents
02 engineering and technology
010402 general chemistry
01 natural sciences
DNA Adducts
chemistry.chemical_compound
medicine
Humans
General Materials Science
Cisplatin
General Engineering
DNA
Hyperthermia, Induced
Glutathione
Prodrug
021001 nanoscience & nanotechnology
0104 chemical sciences
Cross-Linking Reagents
chemistry
Mechanism of action
Cancer cell
Biophysics
Click chemistry
medicine.symptom
0210 nano-technology
Intracellular
medicine.drug
Subjects
Details
- ISSN :
- 1936086X and 19360851
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- ACS Nano
- Accession number :
- edsair.doi.dedup.....ac949ae6fc1355995af67fb8e5bba844