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Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids
- Source :
- Curr Protoc Stem Cell Biol
- Publication Year :
- 2020
-
Abstract
- The homeostatic proliferation-differentiation gradient in the esophageal epithelium is perturbed under inflammatory disease conditions such as gastroesophageal reflux disease and eosinophilic esophagitis. Herein we describe the protocols for rapid generation (
- Subjects :
- 0301 basic medicine
medicine.medical_treatment
Biopsy
Biology
Models, Biological
Article
Proinflammatory cytokine
Flow cytometry
03 medical and health sciences
Mice
0302 clinical medicine
Esophagus
medicine
Organoid
Animals
Homeostasis
Humans
Eosinophilic esophagitis
Cryopreservation
medicine.diagnostic_test
Epithelial Cells
Cell Biology
General Medicine
Eosinophilic Esophagitis
medicine.disease
Epithelium
Organoids
030104 developmental biology
medicine.anatomical_structure
Cytokine
Cancer research
030217 neurology & neurosurgery
Ex vivo
Developmental Biology
Subjects
Details
- ISSN :
- 19388969
- Volume :
- 52
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Current protocols in stem cell biology
- Accession number :
- edsair.doi.dedup.....ac8b693e024df0cbfbeaa488f1372c87