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Tetrahydrogestrinone analysis and designer steroids revisited
- Source :
- Bioanalysis. 1(8)
- Publication Year :
- 2010
-
Abstract
- Anabolic steroids are the main abused class of prohibited substances in doping control. These steroids are associated with enhancement of muscular mass and aggressiveness, resulting in increased performance. Chromatography and MS have a key role among methods developed to detect anabolic steroids in doping control laboratories. However, the classical analytical approach fails in detection of the so-called ‘designer steroids’. This review focuses on the rise of tetrahydrogestrinone, a drug that became synonymous with designer steroids. The reasons why classical methods fail in tetrahydrogestrinone detection are discussed and how the detection was implemented is shown. Alternative strategies for detection of new drugs designed to cheat current analytical methodology are highlighted. Concern for the abuse of veterinary designer drugs and supplements is also acknowledged.
- Subjects :
- Doping in Sports
Gestrinone
Computer science
medicine.drug_class
Clinical Biochemistry
Tetrahydrogestrinone
Veterinary Drugs
General Medicine
Pharmacology
Chemistry Techniques, Analytical
Analytical Chemistry
Designer Drugs
Designer drug
Substance Abuse Detection
Medical Laboratory Technology
Anabolic Agents
Risk analysis (engineering)
Dietary Supplements
medicine
Humans
General Pharmacology, Toxicology and Pharmaceutics
medicine.drug
Subjects
Details
- ISSN :
- 17576199
- Volume :
- 1
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Bioanalysis
- Accession number :
- edsair.doi.dedup.....ac8a87f3493121fe97f07fb7f48767a8