Back to Search
Start Over
Approach to the Patient
- Source :
- Journal of Clinical Endocrinology and Metabolism, 105, Journal of Clinical Endocrinology and Metabolism, 105, 9, Journal of Clinical Endocrinology and Metabolism, 105(9):dgaa441, 3088-3102. ENDOCRINE SOC
- Publication Year :
- 2020
-
Abstract
- Contains fulltext : 225527.pdf (Publisher’s version ) (Closed access) Pheochromocytomas and sympathetic paraganglioma (PPGL) are rare chromaffin cell tumors originating in the adrenal medulla and sympathetic paraganglia, respectively, which share the capacity to synthesize and release catecholamines. The incidence of PPGL has increased in recent years. Surgical resection is the only curative treatment for PPGL. Management of patients with PPGL is complex and should be done by a specialized multidisciplinary team in centers with broad expertise. Surgical resection of a PPGL is a high-risk procedure for which optimal pretreatment with antihypertensive drugs is required in combination with state-of-the-art surgical procedures and anesthesiological techniques. In this article we discuss the underlying evidence and the pros and cons of presurgical medical preparation. Finally, the areas of uncertainty and controversies in this field are addressed.
- Subjects :
- sympathetic paraganglioma
Endocrinology, Diabetes and Metabolism
Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]
Clinical Biochemistry
Adrenal Gland Neoplasms
Sympathetic paraganglia
Biochemistry
0302 clinical medicine
Endocrinology
Patient-Centered Care
HALOTHANE ANESTHESIA
Perioperative management
Vascular damage Radboud Institute for Molecular Life Sciences [Radboudumc 16]
perioperative management
HYPERTENSIVE RESPONSE
Combined Modality Therapy
pheochromocytoma
EUROPEAN-SOCIETY
medicine.anatomical_structure
Curative treatment
030220 oncology & carcinogenesis
LAPAROSCOPIC ADRENALECTOMY
Female
medicine.medical_specialty
030209 endocrinology & metabolism
PREOPERATIVE PREPARATION
Drug Administration Schedule
Perioperative Care
Paraganglioma
Pheochromocytoma
Young Adult
03 medical and health sciences
Internal medicine
medicine
Humans
Perioperative Period
Antihypertensive Agents
Sympathetic Paraganglioma
CALCIUM-CHANNEL BLOCKERS
ANESTHETIC MANAGEMENT
Paraganglia, Chromaffin
business.industry
HEMODYNAMIC INSTABILITY
General surgery
Biochemistry (medical)
alpha-receptor blockade
Surgical procedures
medicine.disease
ALPHA-METHYLTYROSINE
Autonomic Nervous System Diseases
Chromaffin cell
HISTAMINE-RELEASE
Alpha-Methyltyrosine
business
Subjects
Details
- Language :
- English
- ISSN :
- 0021972X
- Volume :
- 105
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Endocrinology and Metabolism
- Accession number :
- edsair.doi.dedup.....ac770813a6ab36a9844fdd135b4359c0