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Current clinical application of sclera and amniotic membrane for ocular tissue bio-replacement
- Source :
- CELL AND TISSUE BANKING, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, instname
- Publication Year :
- 2020
- Publisher :
- SPRINGER, 2020.
-
Abstract
- To report the current clinical applications and trends of scleral and amniotic membrane use in ophthalmology. Review of annual reports from the Catalan Transplant Organization (OCATT), on scleral patch and amniotic membrane eye indications in Catalonia region (Spain) over a 6-year period from 2013 to 2018. A total of 874 scleral and 1665 amniotic membranes patches were implanted, from January 2013 to December 2018. The most frequent indication over the 6-year period for scleral patch was glaucoma surgery (77.5%), eyelid reconstruction (5.2%) and corneal or scleral ulcer (5%). Regarding amniotic membrane, corneal ulcer (26.9%), conjunctival reconstruction (23.8%) and corneal epithelial defect (22.7%) were the most common indications. During the study period, an increasing trend was found on sclera patches for eyelid reconstruction (p = 0.0032) and amniotic membrane for inflammation management (p = 0.0198). Glaucoma surgery and corneal ulcers have represented the top indications for scleral patch and amniotic membrane use, over the period, respectively. A significant trend has also been found towards eyelid reconstruction using scleral patches and amniotic membrane for anterior segment inflammation management. This evolving scenario in tissue use for ocular surgery has to be taken into consideration, especially regarding eye banks facing current and futures changes in tissue preservation, storage and indications.
- Subjects :
- medicine.medical_specialty
genetic structures
Epidemiology
medicine.medical_treatment
Ocular surgery
Scleral transplant
Tissue bank
Biomedical Engineering
Eye bank
Eye Banks
Biomaterials
03 medical and health sciences
Ocular tissue
Glaucoma surgery
0302 clinical medicine
Ophthalmology
Eyelid reconstruction
medicine
Humans
Amnion
030222 orthopedics
Transplantation
business.industry
Cell Biology
corneal ulcer
medicine.disease
eye diseases
Sclera
medicine.anatomical_structure
030221 ophthalmology & optometry
sense organs
Eyelid
business
Subjects
Details
- ISSN :
- 13899333
- Database :
- OpenAIRE
- Journal :
- CELL AND TISSUE BANKING, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, instname
- Accession number :
- edsair.doi.dedup.....ac59c3e6ec7200b0707e2522eb54bd51