Back to Search
Start Over
Antimicrobial Activity of Extracts and Isoquinoline Alkaloids of Selected Papaveraceae Plants
- Source :
- ResearcherID, Scopus-Elsevier
-
Abstract
- Alkaloidal extracts of seven selected plants of the family Papaveraceae were studied with respect to their activity against six strains of pathogenic bacteria and their alkaloidal fingerprint. Twenty-four alkaloids were determined by GC/MS, and twenty of them identified from their mass spectra, retention times and retention indexes. In the antibacterial assay, three Gram-positive ( Enterorococcus faecalis, Staphylococcus aureus and S. hyicus), and three Gram-negative ( Escherichia coli, Proteus mirabilis and Pseudomonas aeruginosa) strains were used. The most promising antimicrobial activity was shown by the alkaloidal extract of Macleaya cordata with MIC values of 16 μg/mL for Staphylococcus aureus, 32 μg/mL for Enterococcus faecalis and 64 μg/mL for Staphylococcus hyicus and Escherichia coli. All the tested pure isoquinoline alkaloids were considered inactive within the tested concentrations.
- Subjects :
- Plant Science
Microbial Sensitivity Tests
medicine.disease_cause
Enterococcus faecalis
Gas Chromatography-Mass Spectrometry
Microbiology
Alkaloids
Anti-Infective Agents
Papaveraceae
Drug Discovery
medicine
heterocyclic compounds
Escherichia coli
Staphylococcus hyicus
Pharmacology
Macleaya cordata
biology
Plant Extracts
General Medicine
biology.organism_classification
Antimicrobial
Isoquinolines
Proteus mirabilis
Complementary and alternative medicine
Staphylococcus aureus
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- ResearcherID, Scopus-Elsevier
- Accession number :
- edsair.doi.dedup.....ac394629473493088aa6ce1edc766296