Should We Consider Deep Brain Stimulation Discontinuation in Late-Stage Parkinson's Disease?

Authors :: Tommaso Tufo
Margherita Fabbri
Romito Luigi
Linda Borellini
Nicola Modugno
Andrea Bruno
Elisa Montanaro
Leonardo Lopiano
Gianluca Ardolino
Filippo Cogiamanian
Paola Berchialla
Carlo Alberto Artusi
Maurizio Zibetti
Antonella Peppe
Carla Piano
Mario Giorgio Rizzone
Brigida Minafra
Claudio Pacchetti
Giulia Giannini
Alberto Romagnolo
Roberto Eleopra
Giovanna Calandra-Buonaura
Alessandro Stefani
Francesco Bove
Pietro Cortelli
Fabbri M.
Zibetti M.
Rizzone M.G.
Giannini G.
Borellini L.
Stefani A.
Bove F.
Bruno A.
Calandra Buonaura G.
Modugno N.
Piano C.
Peppe A.
Ardolino G.
Romagnolo A.
Artusi C.A.
Berchialla P.
Montanaro E.
Cortelli P.
Luigi R.
Eleopra R.
Minafra B.
Pacchetti C.
Tufo T.
Cogiamanian F.
Lopiano L.
Source :: Movement disorders : official journal of the Movement Disorder SocietyReferences. 35(8)
Publication Year :: 2020
Abstract: Background: Subthalamic deep brain stimulation (STN-DBS) effects may decrease with Parkinson’s disease (PD) progression. There is no indication if, when, and how to consider the interruption of DBS treatment in late-stage PD. The objective of the current study was to investigate the percentage of “poor stimulation responders” among late-stage PD patients for elaborating an algorithm to decide whether and when DBS discontinuation may be considered. Methods: Late-stage PD patients (Hoehn Yahr stage ≥4 and Schwab and England Scale

ISSN :: 15318257
Volume :: 35
Issue :: 8
Database :: OpenAIRE
Journal :: Movement disorders : official journal of the Movement Disorder SocietyReferences
Accession number :: edsair.doi.dedup.....ac2a821d4f39903895aeadeb57e588f4

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