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Human Papillomavirus (HPV) Infection in Early Pregnancy: Prevalence and Implications
- Source :
- Infectious Diseases in Obstetrics and Gynecology, Infectious Diseases in Obstetrics and Gynecology, Vol 2019 (2019)
- Publication Year :
- 2019
- Publisher :
- Hindawi, 2019.
-
Abstract
- Introduction. Young women (20-35 years) are at high risk of HPV infection, although the majority of the infections are asymptomatic and are cleared spontaneously by the host immune system. These are also the group of women who are sexually active and are in the population of pregnant women. During pregnancy, the changes in the hormonal milieu and immune response may favor persistence of HPV infection and may aid in transgenerational transmission thereby furthering the cancer risk. In the present study, we determined the prevalence of vaginal HPV infection in early pregnancy and attempted to relate with pregnancy outcome. Material and Methods. Vaginal cytology samples were collected from the condoms used to cover the vaginal sonography probe during a routine first trimester visit to the hospital. All women were followed up throughout pregnancy and childbirth. Maternal and neonatal outcomes were recorded. Results. We found a prevalence of HPV infection around 39.4% in our population. Interestingly all HPV positive women were infected with one or more high risk HPV viruses with an overlap of intermediate and low risk in 43% and 7.3%, respectively. Women with preterm prelabor rupture of membranes (PPROM) showed a statistically higher incidence in HPV positive (7.3%) group as compared to the HPV negative (3.2%) group. Conclusion. The prevalence of genital HPV infection is high during pregnancy (around 40%) and was associated with higher incidence of PPROM.
- Subjects :
- Adult
medicine.medical_specialty
Fetal Membranes, Premature Rupture
Article Subject
Population
Dermatology
lcsh:Gynecology and obstetrics
Asymptomatic
lcsh:Infectious and parasitic diseases
Cohort Studies
03 medical and health sciences
Young Adult
0302 clinical medicine
Pregnancy
medicine
Prevalence
Rupture of membranes
Childbirth
Humans
lcsh:RC109-216
Sex organ
030212 general & internal medicine
Prospective Studies
Pregnancy Complications, Infectious
education
lcsh:RG1-991
education.field_of_study
030219 obstetrics & reproductive medicine
Obstetrics
business.industry
Incidence (epidemiology)
Papillomavirus Infections
HPV infection
Pregnancy Outcome
Obstetrics and Gynecology
medicine.disease
Infectious Diseases
Female
medicine.symptom
business
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 10647449
- Database :
- OpenAIRE
- Journal :
- Infectious Diseases in Obstetrics and Gynecology
- Accession number :
- edsair.doi.dedup.....abe7823130e70eda3672245f2fbc87c3
- Full Text :
- https://doi.org/10.1155/2019/4376902