Prevalence and Associated Risk Factors of Intestinal Parasitic Infections among Egyptian Patients with Inflammatory Bowel Disease

The global prevalence of inflammatory bowel disease (IBD) is continuously rising, however, a little is known concerning intestinal parasitic infections (IPIs) and (IBD). We aimed to evaluate the prevalence of IPIs among IBD patients, through a case-control study and also, to correlate the positive cases to the socio-demographic risk factors of IPIs among the study groups. A 1-year case-control study included patients with IBD (n=125) and healthy controls (n=125). The fecal samples were examined with the classical parasitological methods for intestinal parasites. Also, in-vitro culture (for Blastocystis sp.) and Immuno-chromatography technique (for Cryptosporidium / Giardia /Entamoeba) were done. IBD patients had significant higher positivity rate of IPIs compared to healthy controls (Adjusted OR= 9.60, 95% CI: 4.51-20.41, P = 0.0001), with Blastocystis sp., Entamoeba dispar/ histolytica and Cryptosporidium sp. being highly significant in IBD patients. In addition to IBD, living in rural area, with low socio-economic stander, and consumed raw/contaminated food and age group > 50 years old were significant risk factors for IPIs. In conclusion, our results support a possible link between IPIs and IBD.