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Correlates of Delayed Diagnosis among Human Immunodeficiency Virus-Infected Pulmonary Tuberculosis Suspects in a Rural HIV Clinic, South Africa
- Source :
- Tuberculosis Research and Treatment, Vol 2012 (2012), Tuberculosis Research and Treatment, Tuberculosis research and treatment
- Publication Year :
- 2012
- Publisher :
- Hindawi Publishing Corporation, 2012.
-
Abstract
- Background.Delay in pulmonary tuberculosis (PTB) diagnosis is one of the major factors that affect outcome and threatens continued spread of tuberculosis. This study aimed at determining factors associated with delayed PTB diagnosis among human immunodeficiency virus (HIV) infected individuals.Methods.A retrospective observational study was done using clinic records of HIV-infected PTB suspects attending an HIV/AIDS clinic at Tintswalo rural hospital in South Africa (SA) between January 2006 and December 2007. Using routine clinic registers, 480 records were identified.Results.PTB diagnosis delay was found among 77/176 (43.8%) of the patients diagnosed with PTB. The mean delay of PTB diagnosis was 170.6 days; diagnosis delay ranged 1–30 days in 27 (35.1%) patients, 31–180 days in 24 (33.8%) patients; 24 (31.2%) patients remained undiagnosed for ≥180 days. Independent factors associated with delayed diagnosis were: older age >40 years (Odds Ratio (OR) 3.43, 95% CI 1.45–8.08) and virological failure (OR 2.72, 95% CI 1.09–6.74).Conclusion.There is a considerable delayed PTB diagnosis among HIV-infected patients in rural SA. Older patients as well as patients with high viral load are at a higher risk of PTB diagnosis delay. Therefore efforts to reduce PTB diagnosis delay need to emphasised.
- Subjects :
- Pediatrics
medicine.medical_specialty
Tuberculosis
Article Subject
030231 tropical medicine
wc_503_5
Human immunodeficiency virus (HIV)
lcsh:Medicine
wc_503
medicine.disease_cause
Delayed diagnosis
03 medical and health sciences
0302 clinical medicine
Acquired immunodeficiency syndrome (AIDS)
Pulmonary tuberculosis
Medicine
030212 general & internal medicine
integumentary system
business.industry
lcsh:R
Retrospective cohort study
Odds ratio
medicine.disease
3. Good health
Clinical Study
wf_220
business
wf_300
Viral load
Subjects
Details
- Language :
- English
- ISSN :
- 2090150X
- Database :
- OpenAIRE
- Journal :
- Tuberculosis Research and Treatment
- Accession number :
- edsair.doi.dedup.....ab9f71912336e167157ab52b8d30eef8
- Full Text :
- https://doi.org/10.1155/2012/827148