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Enhancement of BCAT2-Mediated Valine Catabolism Stimulates β-Casein Synthesis via the AMPK-mTOR Signaling Axis in Bovine Mammary Epithelial Cells

Authors :
Xinling Wang
Jie Xu
Hanfang Zeng
Zhaoyu Han
Source :
Journal of Agricultural and Food Chemistry. 70:9898-9907
Publication Year :
2022
Publisher :
American Chemical Society (ACS), 2022.

Abstract

Valine, a kind of branched-chain amino acid, plays a regulatory role beyond that of a building block in milk protein synthesis. However, the underlying molecular mechanism through which valine stimulates β-casein synthesis has not been clarified. Therefore, our study aimed to evaluate the effect of valine on β-casein synthesis and shed light into the molecular mechanism using an

Details

ISSN :
15205118 and 00218561
Volume :
70
Database :
OpenAIRE
Journal :
Journal of Agricultural and Food Chemistry
Accession number :
edsair.doi.dedup.....ab7a4c42690661b62d700a8fecf6aeb1