Marked zinc activation of ester hydrolysis by a mutation, 67-His (CAT) to Arg (CGT), in the active site of human carbonic anhydrase I

Authors :: Ya-Shiou L. Yu
Patrick J. Venta
Lynn E. Wagner
Nils Bergenhem
W. Richard Chegwidden
Richard E. Tashian
Source :: Human Mutation. 4:294-296
Publication Year :: 1994
Publisher :: Hindawi Limited, 1994.

Subjects :: biology
Hydrolysis
DNA Mutational Analysis
Active site
chemistry.chemical_element
Ester hydrolysis
Zinc
Polymerase Chain Reaction
Enzyme Activation
chemistry
Biochemistry
Mutation (genetic algorithm)
Genetics
biology.protein
Humans
Point Mutation
Carbonic Anhydrase I
Genetics (clinical)
Carbonic Anhydrases

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