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Supplementary Figure 1 from SHP2 Inhibition Overcomes RTK-Mediated Pathway Reactivation in KRAS-Mutant Tumors Treated with MEK Inhibitors
- Publication Year :
- 2023
- Publisher :
- American Association for Cancer Research (AACR), 2023.
-
Abstract
- Schematic illustration of MEKi-induced MAPK pathway feedback activation, SHP099 dose-dependent reduction of p-MEK induction by MEKi, and MEKi-induced p-AKT levels.
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....ab33e010e3ab7eccd5822273f9c9b791
- Full Text :
- https://doi.org/10.1158/1535-7163.22506412