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trans-3-n-propyl-L-proline is a highly favorable, conformationally restricted replacement for methionine in the C-terminal tetrapeptide of cholecystokinin. Stereoselective synthesis of 3-allyl- and 3-n-propyl-L-proline derivatives from 4-hydroxy-L-proline
- Source :
- Journal of medicinal chemistry. 34(1)
- Publication Year :
- 1991
- Subjects :
- Cerebral Cortex
Methionine
Tetrapeptide
Molecular Structure
Proline
Chemistry
Stereochemistry
Guinea Pigs
4-Hydroxy-L-proline
Tetragastrin
chemistry.chemical_compound
Hydroxyproline
Structure-Activity Relationship
Drug Discovery
Molecular Medicine
Animals
Stereoselectivity
Indicators and Reagents
Receptors, Cholecystokinin
Pancreas
Cholecystokinin
Subjects
Details
- ISSN :
- 00222623
- Volume :
- 34
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of medicinal chemistry
- Accession number :
- edsair.doi.dedup.....aaa67ce53be3da20a20a94fad6200f41