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An immunohistochemical and ultrastructural study of an unusual case of multiple non-X histiocytoma
- Source :
- Archives of dermatology. 124(8)
- Publication Year :
- 1988
-
Abstract
- • An immunohistochemical and ultrastructural study of an atypical case of multiple non-X histiocytoma was done. There was involvement of the skin, lungs, and liver in a 3-month-old male infant. Microscopic examination of the cutaneous tumors revealed a dense infiltration of cells with polymorphous large nuclei and abundant eosin-ophilic cytoplasm in the entire dermis. Both immunohistochemical and electron microscopic studies suggested that the tumors were non-X histiocytomas. The patient's condition deteriorated with dyspnea due to rapid enlargement of tumor masses in the liver and lungs. However, at 5 months of age, the cutaneous nodules and pulmonary and hepatic lesions showed a tendency to involute. Furthermore, at 12 months of age, they were no longer detectable. The patient at 24 months of age was well with normal development. To date, no recurrence of the disease has been observed. (Arch Dermatol1988;124:1254-1257)
- Subjects :
- Male
Pathology
medicine.medical_specialty
Lung Neoplasms
Skin Neoplasms
Biopsy
Dermatology
Fibroma
medicine
Humans
Entire dermis
Electron microscopic
Unusual case
business.industry
Liver Neoplasms
Cutaneous nodules
Infant
General Medicine
Anatomy
medicine.disease
Immunohistochemistry
Cutaneous tumors
Neoplasm Regression, Spontaneous
Ultrastructure
business
Infiltration (medical)
Subjects
Details
- ISSN :
- 0003987X and 12541257
- Volume :
- 124
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Archives of dermatology
- Accession number :
- edsair.doi.dedup.....aa3ca2b64d8c4a62439f80ec8711530f