Fibrodysplasia Ossificans Progressiva Detected on FDG PET/CT

Fibrodysplasia ossificans progressiva (FOP) is a genetic disorder of the skeletal system which, due to its rarity, is frequently misdiagnosed for a malignancy (Kitterman et al. Pediatrics. 2005;116:e654–e661). Consequently, these patients are subjected to multiple invasive diagnostic and therapeutic procedures which instead can aggravate the disease (Kitterman et al. Pediatrics. 2005;116:e654–e661). Recognition of the computed tomography appearance of FOP is thus vital, as these patients are likely to be referred for a positron emission tomography/computed tomography (PET/CT) to stage a misdiagnosed cancer. In this study, the PET/CT features of FOP are demonstrated in a child who was referred for staging of an erroneously diagnosed lymphoma.