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Relationship between fractional pancreatic beta cell area and fasting plasma glucose concentration in monkeys

Authors :
Erica Manesso
Claudio Cobelli
Kylie Kavanagh
Pc Butler
Tatyana Gurlo
Ryan Galasso
Ae Butler
Jd Wagner
Gianna Toffolo
Li Zhang
Yoshifumi Saisho
Source :
Saisho, Y.; Butler, A. E.; Manesso, E.; Galasso, R.; Zhang, L.; Gurlo, T.; et al.(2010). Relationship between fractional pancreatic beta cell area and fasting plasma glucose concentration in monkeys. Diabetologia: Clinical and Experimental Diabetes and Metabolism, 53(1), pp 111-114. doi: 10.1007/s00125-009-1552-z. Retrieved from: http://www.escholarship.org/uc/item/65q33744, Diabetologia
Publication Year :
2010

Abstract

Aims/hypothesis We sought to establish the relationship between fasting plasma glucose concentrations and pancreatic fractional beta cell area in adult cynomolgus monkeys (Macaca fascicularis). Methods Fasting plasma glucose and pancreatic fractional beta cell area were measured in 18 control and 17 streptozotocin-treated adult primates (17.0 ± 1.2 vs 15.4 ± 1.2 years old). Results Fasting plasma glucose was increased (12.0 ± 2.0 vs 3.4 ± 0.1 mmol/l, p

Details

Language :
English
Database :
OpenAIRE
Journal :
Saisho, Y.; Butler, A. E.; Manesso, E.; Galasso, R.; Zhang, L.; Gurlo, T.; et al.(2010). Relationship between fractional pancreatic beta cell area and fasting plasma glucose concentration in monkeys. Diabetologia: Clinical and Experimental Diabetes and Metabolism, 53(1), pp 111-114. doi: 10.1007/s00125-009-1552-z. Retrieved from: http://www.escholarship.org/uc/item/65q33744, Diabetologia
Accession number :
edsair.doi.dedup.....aa1392ec6b03ed6cd2a4585c4cc376a1
Full Text :
https://doi.org/10.1007/s00125-009-1552-z.