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Assessment of total vascular resistance and total body water in normotensive women during the first trimester of pregnancy. A key for the prevention of preeclampsia
- Source :
- Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 5:193-197
- Publication Year :
- 2015
- Publisher :
- Elsevier BV, 2015.
-
Abstract
- Introduction Maternal cardiovascular system adapts to pregnancy, thanks to complex physiological mechanisms that involve cardiac output, total vascular resistance and water body distribution. Abnormalities of these adaptive mechanisms are connected with hypertensive disorders. Objective To identify patients at a high risk of developing hypertensive complications of pregnancy during the first trimester of pregnancy, through the use of non-invasive methods such as USCOM (Ultrasonic Cardiac Output Monitor) and Bioimpedance. Materials and methods We enrolled 120 healthy normotensive women during the first trimester of pregnancy obtaining all measurements with the USCOM system and Bioimpedance. Results 20 patients were excluded for a bad USCOM signal. The remaining patients ( n =100) were retrospectively divided into two groups: Group A ( n =75) TVR −5 , Group B ( n =25) TVR>1200dynesscm −5 . No statistically significant difference was identified in terms of water distribution, Fat Free Mass, Systolic/Diastolic Blood Pressure, Heart Rate, Hematocrit, Flow Time Corrected and Water Balance Index between the two groups. In contrast, higher values of the Cardiac Output, Stroke Volume, Fat Mass and Inotropy Index have been highlighted in the Group A. Moreover, in the Group A we found a better maternal–neonatal outcome and a lower incidence of hypertensive complications. Conclusions High TVR during the first weeks of gestation may be an early marker of cardiovascular maladaptation more than the evaluation of water distribution and, in particular, with respect to the single blood pressure assessment. Moreover lower values of Inotropy Index could be an indicative of the worst cardiac performance.
- Subjects :
- Adult
medicine.medical_specialty
Cardiac output
Complications of pregnancy
Blood Pressure
Gestational hypertension
Hematocrit
Settore BIO/09
Preeclampsia
Body Water
Pre-Eclampsia
Heart Rate
Pregnancy
Internal medicine
Electric Impedance
Internal Medicine
medicine
Humans
Early and late preeclampsia
Prospective Studies
Early pregnancy
Bioimpedance
medicine.diagnostic_test
business.industry
Obstetrics and Gynecology
Stroke Volume
Hypertension, Pregnancy-Induced
Stroke volume
medicine.disease
Total vascular resistance
Surgery
Pregnancy Trimester, First
medicine.anatomical_structure
Blood pressure
Vascular resistance
Cardiology
Inotropy index
Female
Vascular Resistance
Settore MED/40 - Ginecologia e Ostetricia
business
Subjects
Details
- ISSN :
- 22107789
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health
- Accession number :
- edsair.doi.dedup.....aa00f1375248c31fe74c55f3877489c1