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Algorithm to rule out clinically significant portal hypertension combining Shear-wave elastography of liver and spleen : a prospective multicentre study
- Source :
- Gut : the journal of the British Society for Gastroenterology, Jansen, C, Bogs, C, Verlinden, W, Thiele, M, Möller, P, Görtzen, J, Lehmann, J, Praktiknjo, M, Chang, J, Krag, A, Strassburg, C P, Francque, S & Trebicka, J 2016, ' Algorithm to rule out clinically significant portal hypertension combining Shear-wave elastography of liver and spleen : a prospective multicentre study ', Gut, vol. 65, no. 6, pp. 1057-1058 . https://doi.org/10.1136/gutjnl-2016-311536
- Publication Year :
- 2016
-
Abstract
- Recently, the UK guidelines on variceal bleeding1 and other reports have introduced the role of elastography for the diagnosis of oesophageal varices (OVs).2 ,3 Development of OVs is likely when the hepatic venous pressure gradient is higher than 10 mm Hg, which defines clinically significant portal hypertension (CSPH). Baveno VI implemented transient elastography (TE) as a tool to rule in CSPH in viral aetiologies and to rule out varices (need of screening endoscopy for varices).4 Furthermore, CSPH has a strong prognostic value in patients with cirrhosis. Recent studies introduced Shear-wave elastography of the liver (L-SWE) as a promising tool to diagnose portal hypertension. These studies find good diagnostic accuracy of L-SWE with specificity and sensitivity ranging around 80% and superior to TE. However, in more than 30% of the patients CSPH could not be ruled in or ruled out, since their SWE values were between the cut-offs. This prospective multicentre study investigated the …
- Subjects :
- Liver Cirrhosis
medicine.medical_specialty
Cirrhosis
Portal venous pressure
Esophageal and Gastric Varices
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Internal medicine
Hypertension, Portal
medicine
Humans
Prospective Studies
Prospective cohort study
medicine.diagnostic_test
business.industry
medicine.disease
Endoscopy
Liver
030220 oncology & carcinogenesis
Portal hypertension
Elasticity Imaging Techniques
030211 gastroenterology & hepatology
Radiology
Elastography
Human medicine
Varices
Transient elastography
business
Algorithms
Spleen
Subjects
Details
- Language :
- English
- ISSN :
- 00175749
- Database :
- OpenAIRE
- Journal :
- Gut : the journal of the British Society for Gastroenterology
- Accession number :
- edsair.doi.dedup.....a9e0c42de1ec3c5cd38a5127b44f0f25