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Systemic production of nitric oxide during severe asthma: immonumodulation by the helminth echinococcus granulosus
- Source :
- Clinical and Translational Allergy
- Publication Year :
- 2015
- Publisher :
- Wiley, 2015.
-
Abstract
- Background Several studies highlight the implication of nitric oxide (NO) in the airways inflammation during asthma. Moreover, asthma is thought to be associated with a systemic inflammation. However, little is known about the systemic production of NO in asmathic patients. In this sense, our aim was to evaluate the in vivo and ex vivo production of NO in Algerian patients with severe asthma. Moreover, the effect of helminthes infection on asthma is still inconclusive. In this sense, the second part of this study aims to investigate the effect of the helminth Echinococcus granulosus on this production. This parasite causes cyst formation particularly in lungs and liver.
- Subjects :
- Pulmonary and Respiratory Medicine
Allergy
biology
business.industry
Immunology
Inflammation
medicine.disease
biology.organism_classification
Systemic inflammation
respiratory tract diseases
Nitric oxide
chemistry.chemical_compound
chemistry
Poster Presentation
parasitic diseases
medicine
Immunology and Allergy
Helminths
medicine.symptom
business
Echinococcus granulosus
Ex vivo
Asthma
Subjects
Details
- ISSN :
- 20457022
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Clinical and Translational Allergy
- Accession number :
- edsair.doi.dedup.....a9a5063108aebbe9d522ab59a8ea2bba