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Differential expression of genes linked to the leukemia inhibitor factor signaling pathway during the estrus cycle and early pregnancy in the porcine endometrium
- Source :
- Reproductive Biology. 14:293-297
- Publication Year :
- 2014
- Publisher :
- Elsevier BV, 2014.
-
Abstract
- The objective of this study was to determine the expression profiles of leukemia inhibitory factor (LIF) and its receptor (LIFR), interleukin 6 receptor (IL6R), tumor protein p53 (TP53) and B-cell CLL/lymphoma 2 (BCL2) in the porcine endometrium on selected days of the estrous cycle and pregnancy. Time- and reproductive status (estrous cycle/pregnancy)-specific patterns of expression were identified for all investigated genes. The most pronounced changes were seen on Days 12 and 14 of pregnancy when maternal recognition of pregnancy and implantation, respectively, occurs in pigs.
- Subjects :
- medicine.medical_specialty
Receptors, OSM-LIF
Swine
Estrous Cycle
Leukemia inhibitory factor receptor
Biology
Real-Time Polymerase Chain Reaction
Endometrium
Leukemia Inhibitory Factor
Endocrinology
Pregnancy
hemic and lymphatic diseases
Internal medicine
medicine
Animals
Receptor
reproductive and urinary physiology
Estrous cycle
Analysis of Variance
urogenital system
Gene Expression Profiling
Gene Expression Regulation, Developmental
medicine.disease
Receptors, Interleukin-6
Leukemia
medicine.anatomical_structure
Proto-Oncogene Proteins c-bcl-2
Interleukin-6 receptor
Female
Animal Science and Zoology
Tumor Suppressor Protein p53
Leukemia inhibitory factor
Signal Transduction
Developmental Biology
Subjects
Details
- ISSN :
- 1642431X
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Reproductive Biology
- Accession number :
- edsair.doi.dedup.....a97f3a19f3fad1bff2da6e70894a9d23