Back to Search
Start Over
Improving the aseptic transfer procedures in hospital pharmacies part C
- Source :
- European Journal of Hospital Pharmacy, European Journal of Hospital Pharmacy: Science and Practice, 29(1), 12-17. BMJ PUBLISHING GROUP, European Journal of Hospital Pharmacy, 29(1), 12-17. BMJ PUBLISHING GROUP
- Publication Year :
- 2022
- Publisher :
- BMJ PUBLISHING GROUP, 2022.
-
Abstract
- OBJECTIVES: To transfer sterile medical devices (SMD), infusion bags (IB), ampoules (A), injection vials (V) and infusion bottles (B) into a laminar airflow cabinet (LAF) or safety cabinet (SC) with a surface bioburden as low as possible.METHODS: Surface bioburden of the outer layer of SMD, IB, A, V and B was determined by contact plates. Surface bioburden determination of critical spots on A, V and B (ampoule necks and stoppers) was determined by high-recovery swabs and contact plates. Particle emission from white cardboard boxes was determined by a particle counter.RESULTS: The chances of a contaminated outer layer of SMD is negligible as long as they stay in their original boxes. The outer layer of double-packed IB can contain a considerable number of micro-organisms. As found in previous studies, the surface bioburden of A, V and B is low as long as they stay in their original cardboard boxes. Particle emission from white boxes is low. The necessity of a final disinfection step inside LAF/SC of critical sspots of A, V and B cannot be proven. SmallSMD, ampoules and injection vials can be transferred into the background areain their original white boxes. Other materials have to be unpacked in front ofthe lock while the operator wear disposable gloves. Disinfection of the outerlayer of IB, before transfer trough the lock, is advised. Tohave materials with a low chance of contamination in LAF/SC, transfer bypresentation for SMD and IB and using a sterile tray for disinfected materialsis an effective procedure. Wiping of ampoule necks and stoppers inside LAF/SC isadvised based on risk assessment.Small SMD, ampoules and injection vials can be transferred into the background areain their original white boxes. Other materials have to be unpacked in front ofthe lock while the operator wear disposable gloves. Disinfection of the outerlayer of IB, before transfer trough the lock, is advised.CONCLUSION: When SMD, ampoules, injection vials and infusion bottles stay in their original boxes as long as possible, the aseptic transfer and the disinfection procedure can be maintained effectively and efficiently.
- Subjects :
- Pharmacies
Materials science
aseptic handling
surface bioburden
030226 pharmacology & pharmacy
Ampoule
Hospitals
Bioburden
Disinfection
03 medical and health sciences
0302 clinical medicine
Tray
Particle emission
aseptic transfer process
sterile medical device
030212 general & internal medicine
Aseptic processing
particle emission
General Pharmacology, Toxicology and Pharmaceutics
Composite material
Drug Contamination
Original Research
Subjects
Details
- Language :
- English
- ISSN :
- 20479956
- Database :
- OpenAIRE
- Journal :
- European Journal of Hospital Pharmacy, European Journal of Hospital Pharmacy: Science and Practice, 29(1), 12-17. BMJ PUBLISHING GROUP, European Journal of Hospital Pharmacy, 29(1), 12-17. BMJ PUBLISHING GROUP
- Accession number :
- edsair.doi.dedup.....a9771f803d658d09ff07a2aa6de64c26