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Clinical value of multidetector row computed tomography in detecting lymph node metastasis of early gastric cancer
- Source :
- European Journal of Surgical Oncology (EJSO). 31:743-748
- Publication Year :
- 2005
- Publisher :
- Elsevier BV, 2005.
-
Abstract
- To evaluate the clinical value of multidetector row computed tomography (MDCT) as a pre-operative staging tool for lymph node metastasis in patients with early gastric cancer (EGC).In 278 consecutive patients with EGC, lymph node metastasis was evaluated pre-operatively with MDCT at a slice thickness of 2.5mm (n=57), 5.0mm (n=188), or 7.5mm (n=33).Overall accuracy of nodal category from N0 to N3 was 86% for MDCT and 95% for operative assessment. Regarding accuracy in detecting at least one metastatic lymph node, area under curves (AUC) of receiver operating characteristics for 2.5, 5.0, and 7.5-mm slices and assessment during surgery were 0.87, 0.67 and 0.47, and 0.70, which were significantly different (P0.0001). MDCT image with 2.5-mm could discriminate the presence of lymph node metastasis with diagnostic accuracy: sensitivity 80%; specificity 92%; positive predictive value (PPV) 50%; negative predictive value (NPV) 98%, whereas assessment during surgery was as follows: sensitivity 65%; specificity 98%; PPV 72%; and NPV 97%.These results suggest that pre-operative assessment with MDCT using thinner slices may detect at least one lymph node metastasis as accurately as assessment during surgery for patients with EGC.
- Subjects :
- Adult
Male
Stomach neoplasm
medicine.medical_specialty
Computed tomography
Lymph node metastasis
Adenocarcinoma
Sensitivity and Specificity
Predictive Value of Tests
Stomach Neoplasms
Preoperative Care
Area under curve
medicine
Humans
Lymph node
Aged
Neoplasm Staging
Receiver operating characteristic
medicine.diagnostic_test
business.industry
General Medicine
Middle Aged
Early Gastric Cancer
medicine.anatomical_structure
Oncology
Lymphatic Metastasis
Clinical value
Female
Surgery
Radiology
Tomography, X-Ray Computed
business
Subjects
Details
- ISSN :
- 07487983
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- European Journal of Surgical Oncology (EJSO)
- Accession number :
- edsair.doi.dedup.....a94ff117392e7088eca1b69e9d34722d