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OPTICAL COHERENCE TOMOGRAPHIC ANGIOGRAPHY IN CENTRAL SEROUS CHORIORETINOPATHY
- Source :
- Retina. 36:2051-2058
- Publication Year :
- 2016
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2016.
-
Abstract
- Using optical coherence tomographic angiography (OCT-angiography), we examined the vasculature of the choriocapillaris in patients with central serous chorioretinopathy (CSC).The prospective observational clinical study included patients with CSC defined by painless loss of central visual acuity and presence of a serous macular detachment as visualized by spectral-domain OCT. All eyes underwent OCT-angiography. Subfoveal choroidal thickness and choriocapillaris width were measured.The study included 26 eyes of 21 patients with a mean age of 47.0 ± 7.9 years (range: 34-65 years). All 26 eyes showed an image pattern of high signal intensity, and 21 eyes additionally demonstrated dilated capillaries in the OCT-angio images. The areas showing abnormalities in the OCT-angiography were congruent with leaking areas in fluorescein angiography or areas with hyperpermeability in indocyanine green angiography. Among 16 patients with unilateral CSC, 1 patient showed a high intensity pattern in the OCT-angiogram in the contralateral, clinically unaffected eye. Parallel to thicker choroidal thickness measurements in affected eyes as compared with contralateral unaffected eyes in unilateral CSC, OCT-angiography revealed significantly thicker choriocapillaris measurements in the affected eyes. Conventional fluorescein angiography did not demonstrate leakage in 14 of 18 eyes with clinically diagnosed CSC.Optical coherence tomographic angiography showed an image pattern of high signal intensity in all eyes with CSC and dilated vessels in the choriocapillaris in most eyes with clinically diagnosed CSC. The results indicate that OCT-angiography may become a noninvasive valuable tool for the diagnosis of CSC in particular and for the diagnosis of macular disorders in general.
- Subjects :
- Adult
Indocyanine Green
Male
0301 basic medicine
medicine.medical_specialty
Visual acuity
genetic structures
Visual Acuity
Capillary Permeability
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
medicine
Humans
Prospective Studies
Fluorescein Angiography
Coloring Agents
Aged
medicine.diagnostic_test
Choroid
business.industry
General Medicine
Coherence (statistics)
Middle Aged
Fluorescein angiography
eye diseases
Capillaries
Ophthalmology
Serous fluid
030104 developmental biology
medicine.anatomical_structure
Central Serous Chorioretinopathy
chemistry
Angiography
030221 ophthalmology & optometry
Female
sense organs
Radiology
Tomography
medicine.symptom
business
Indocyanine green
Tomography, Optical Coherence
Subjects
Details
- ISSN :
- 0275004X
- Volume :
- 36
- Database :
- OpenAIRE
- Journal :
- Retina
- Accession number :
- edsair.doi.dedup.....a8f5a373b572e67287d60359f2216f71