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Three-Month Psychiatric Outcome of Pediatric Mild Traumatic Brain Injury: A Controlled Study
- Source :
- Journal of neurotrauma, vol 38, iss 23, J Neurotrauma
- Publication Year :
- 2021
- Publisher :
- Mary Ann Liebert Inc, 2021.
-
Abstract
- The objective was to clarify occurrence, phenomenology, and risk factors for novel psychiatric disorder (NPD) in the first 3 months after mild traumatic brain injury (mTBI) and orthopedic injury (OI). Children aged 8-15 years with mTBI (n = 220) and with OI but no TBI (n = 110) from consecutive admissions to an emergency department were followed prospectively at baseline and 3 months post-injury with semi-structured psychiatric interviews to document the number of NPDs that developed in each participant. Pre-injury child variables (adaptive, cognitive, and academic function, and psychiatric disorder), pre-injury family variables (socioeconomic status, family psychiatric history, and family function), and injury severity were assessed and analyzed as potential confounders and predictors of NPD. NPD occurred at a significantly higher frequency in children with mTBI versus OI in analyses unadjusted (mean ratio [MR] 3.647, 95% confidence interval [CI(95)] (1.264, 15.405), p = 0.014) and adjusted (MR = 3.724, CI(95) (1.264, 15.945), p = 0.015) for potential confounders. In multi-predictor analyses, the factors besides mTBI that were significantly associated with higher NPD frequency after adjustment for each other were pre-injury lifetime psychiatric disorder [MR = 2.284, CI(95) (1.026, 5.305), p = 0.043]; high versus low family psychiatric history [MR = 2.748, CI(95) (1.201, 6.839), p = 0.016], and worse socio-economic status [MR = 0.618 per additional unit, CI(95) (0.383, 0.973), p = 0.037]. These findings demonstrate that mild injury to the brain compared with an OI had a significantly greater deleterious effect on psychiatric outcome in the first 3 months post-injury. This effect was present even after accounting for specific child and family variables, which were themselves independently related to the adverse psychiatric outcome.
- Subjects :
- Male
medicine.medical_specialty
Physical Injury - Accidents and Adverse Effects
Adolescent
pediatrics
Traumatic brain injury
Clinical Sciences
Traumatic Brain Injury (TBI)
Psychiatric history
Clinical Research
mild traumatic brain injury
Humans
Medicine
Musculoskeletal Diseases
Child
Prospective cohort study
Psychiatry
Musculoskeletal System
Socioeconomic status
Brain Concussion
Traumatic Head and Spine Injury
Pediatric
Neurology & Neurosurgery
business.industry
Mental Disorders
Confounding
Neurosciences
Original Articles
Emergency department
prospective longitudinal controlled study
medicine.disease
Confidence interval
Brain Disorders
psychiatric disorders
Orthopedic surgery
Female
Mental health
Neurology (clinical)
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 15579042 and 08977151
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- Journal of Neurotrauma
- Accession number :
- edsair.doi.dedup.....a8ca46ebbc44a05fc6bf97d2cd82486e