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Development and Validation of a Novel Fibrosis Marker in Biliary Atresia during Infancy

Authors :
Miwako Nakano
Fumiko Yoshida
Yohei Yamada
Ken Hoshino
Seiya Akatsuka
Hirofumi Tomita
Akihiro Fujino
Yasushi Fuchimoto
Yutaka Kanamori
Yohei Masugi
Tatsuo Kuroda
Mureo Kasahara
Atsuko Nakazawa
Michiie Sakamoto
Source :
Clinical and Translational Gastroenterology
Publication Year :
2015
Publisher :
Ovid Technologies (Wolters Kluwer Health), 2015.

Abstract

Objectives: Most biliary atresia (BA) patients suffer from liver fibrosis and often require liver transplantation. The aim of this study was to develop and validate a novel fibrosis marker for BA patients aged 6 (equivalent to F4) at the initial surgery survived with their native liver at 1 year of age (n=9). Conclusions: The iBALF score that was developed was a good noninvasive marker of native liver fibrosis for BA patients aged

Details

ISSN :
2155384X
Volume :
6
Database :
OpenAIRE
Journal :
Clinical and Translational Gastroenterology
Accession number :
edsair.doi.dedup.....a894f413e3437360ecd111bc610e6c3a
Full Text :
https://doi.org/10.1038/ctg.2015.55